BCN-PEG1-alcohol (CAS 1395786-21-6) is a specialized chemical often used in bioconjugation and drug delivery applications. It has a BCN group and an alcohol group, facilitating copper-free click chemistry. The compound includes a polyethylene glycol (PEG) chain with a single unit (PEG1), which can enhance water solubility and bioavailability while decreasing immunogenicity. The short PEG1 provides an optimal length for efficient molecule conjugation. The BCN terminus enables reactions with azides, useful in biological systems sensitive to copper, while the alcohol end offers a site for further conjugation, such as forming ester bonds with carboxylic acids.
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