Azido-PEG6-Hydrazide
This product is a high-purity heterobifunctional PEG linker with an azide specifically for click chemistry and a hydrazide group for conjugation with aldehydes and ketones. The PEG6 spacer enhances solubility, flexibility, and minimizes steric hindrance, making it well-suited for bioconjugation in aqueous and organic systems.
Key Features and Benefits
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Azide Group – Enables copper-catalyzed (CuAAC) or strain-promoted (SPAAC) click reactions.
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Hydrazide Group – Forms stable hydrazone bonds with aldehydes or ketones for protein, glycan, and surface conjugation.
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PEG6 Spacer – Improves water solubility, biocompatibility, and provides spatial separation between functional groups.
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High Purity – Ensures reliable and reproducible results in advanced synthesis and labeling workflows.
Applications
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Protein and glycoprotein labeling through hydrazone formation
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Dual-functional linker for orthogonal conjugation strategies
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Bioconjugation of antibodies, peptides, or nanoparticles
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Surface modification and biomaterials research
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light
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Use: Dissolve in anhydrous solvents (e.g., DMSO, DMF). Perform azide–alkyne click chemistry or aldehyde/ketone coupling under appropriate conditions.
This product is a heterobifunctional PEG linker combining an azide for click chemistry and a hydrazide for aldehyde/ketone conjugation, specifically connected by a PEG6 spacer for solubility and biocompatibility.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
