Azido-PEG4-(CH2)3OH CAS:2028281-87-8 is a polyethylene glycol (PEG) derivative specifically designed for bioconjugation and pharmaceutical research applications. This compound features an azido (N3) functional group, which is highly reactive and able to undergo efficient click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC). The azido group enables the rapid and selective formation of covalent linkages with complementary functional groups, such as alkynes or strained cyclooctynes, making it an ideal choice for constructing complex bioconjugates.
The PEG4 linker, a tetraethylene glycol, serves as a flexible and biocompatible spacer that connects the azido group to a hydroxyl (OH) group at the other end of the molecule. This hydroxyl group can participate in a wide range of chemical reactions, such as esterification and etherification. The PEG4 linker imparts enhanced water solubility, reduced immunogenicity, and improved pharmacokinetic profiles to the compound, allowing for the development of more effective and targeted therapeutics.
With its unique combination of functional groups and biocompatible linker, Azido-PEG4-(CH2)3OH offers tremendous potential in pharmaceutical research and development. Its versatility enables the creation of advanced drug conjugates, prodrugs, and targeted drug delivery systems, leading to optimized therapies with fewer side effects.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
