Azido-PEG36-t-butyl ester
This product is a heterobifunctional PEG linker with a terminal azide group for click chemistry and an acid-labile t-butyl ester for orthogonal protection. The long PEG36 chain provides exceptional solubility, flexibility, and spacing, making it especially valuable for bioconjugation, probe development, and drug delivery.
Key Features and Benefits:
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Azide Group: Enables CuAAC or SPAAC click chemistry with alkynes.
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t-Butyl Ester: Provides acid-labile protection for stepwise synthesis.
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PEG36 Spacer: Offers excellent solubility, hydrophilicity, and extended flexibility.
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Orthogonal Design: Supports controlled, multifunctional conjugation strategies.
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High Purity: Ensures reproducibility in advanced workflows.
Applications:
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Bioconjugation: Links biomolecules via azide–alkyne chemistry with protected functionality.
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Drug Delivery: Provides PEGylated scaffolds with long circulation and tunable release.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Material Science: Functionalizes polymers and nanomaterials with long PEG arms.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid premature ester cleavage.
This product combines click-ready azide functionality with acid-labile protection in a long PEG36 scaffold, specifically offering superior solubility and spacing for advanced conjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
