Azido-PEG35-amine
This product is a high-purity PEG linker with a terminal azide for click chemistry and a terminal primary amine for versatile conjugation, connected by a long PEG35 spacer specifically for enhanced solubility, hydrophilicity, and reduced steric hindrance.
Key Features and Benefits
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Azide Group – Enables copper-catalyzed (CuAAC) and strain-promoted (SPAAC) click chemistry.
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Primary Amine Group – Reactive site for conjugation with NHS esters, activated carboxyls, and aldehydes.
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PEG35 Spacer – Provides exceptional hydrophilicity, extended reach, and minimizes steric hindrance in bioconjugates.
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High Purity – Suitable for bioconjugation, drug delivery, and diagnostic development.
Applications
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Dual functionalization of proteins, peptides, or antibodies.
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Click chemistry labeling with alkynes.
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Amide bond formation with activated carboxyls.
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Linker for drug conjugates, nanoparticles, and surface modification.
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents (e.g., DMSO, DMF). Avoid repeated freeze–thaw cycles.
Azido-PEG35-amine provides both an azide and a primary amine on a long PEG35 spacer, specifically enabling efficient click chemistry and amide coupling with superior solubility and flexibility.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
