Azido-PEG3-S-PEG3-azide
This product is a symmetric PEG-based linker featuring terminal azide groups on both ends connected by a thioether (–S–) bridge and PEG3 spacers. This design provides solubility, bioorthogonal reactivity, and sulfur-mediated stability, making it especially useful in click chemistry, bioconjugation, and advanced materials.
Key Features and Benefits:
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Dual Azides: Support CuAAC or SPAAC click chemistry with alkynes.
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Thioether Bridge: Adds stability and unique chemical properties.
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PEG3 Spacers: Improve solubility and steric accessibility.
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Symmetric Design: Enables multifunctional and modular conjugation.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications:
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Bioconjugation: Links biomolecules via orthogonal azide–alkyne click chemistry.
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Probe Development: Builds multifunctional probes for diagnostics and imaging.
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Drug Delivery: Provides PEGylated scaffolds with reactive azide handles.
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Material Science: Functionalizes surfaces and polymers with dual click sites.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid reducing conditions.
This product integrates dual azides with a thioether-linked PEG scaffold, specifically offering solubility, symmetry, and versatile reactivity for click chemistry and conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
