Azido-PEG16-Acid (N3-PEG16-CH₂CH₂COOH)
Description:
Azido-PEG16-acid is a PEG-based linker with an azide (N3) functional group on one end and a carboxylic acid (COOH) group on the other. The azide allows for click chemistry with alkyne-containing molecules, while the carboxylic acid enables conjugation to amine groups through amide bond formation. The PEG16 spacer enhances solubility, flexibility, and biocompatibility, making it ideal for various bioconjugation applications.
Key Features:
- Azide Group (N3): Allows for copper-catalyzed or strain-promoted click chemistry with alkyne-functionalized molecules.
- PEG16 Spacer: Provides flexibility, increased solubility, and reduces non-specific interactions.
- Carboxylic Acid Group (COOH): Enables coupling to amine-containing biomolecules for stable amide bond formation.
Applications:
- Bioconjugation: Links biomolecules using azide-alkyne click chemistry and amide bond formation.
- Drug Delivery Systems: Useful in creating PEGylated molecules for improved stability and targeting.
- Nanoparticle and Surface Functionalization: Modifies surfaces or nanoparticles for biomedical applications, improving solubility and biocompatibility.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
