APN-PEG4-tetrazine is a versatile, bifunctional linker that combines an aliphatic primary amine (APN) with a polyethylene glycol (PEG4) spacer and a reactive tetrazine moiety. This chemical compound facilitates site-specific conjugation, enhancing solubility and minimizing immunogenicity, making it a valuable tool in pharmaceutical research and development.
Introduction to the application:
In pharmaceutical R&D, APN-PEG4-tetrazine plays a crucial role in bioorthogonal chemistry, specifically for click chemistry and pretargeted imaging applications. By connecting biomolecules with imaging agents or drug payloads, it enables targeted drug delivery, controlled release, and improved pharmacokinetics. Consequently, this linker is instrumental in the design of next-generation therapeutics and diagnostics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
