Amino-PEG8-t-butyl ester
This product is a heterobifunctional PEG reagent with a reactive terminal amine and an acid-labile t-butyl ester specifically linked by a PEG8 spacer. The PEG chain improves solubility and flexibility, while the t-butyl ester provides controlled deprotection for orthogonal conjugation strategies.
Key Features and Benefits:
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Amine Group: Reacts with carboxyls, NHS esters, and other electrophiles.
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t-Butyl Ester: Acid-labile protection for stepwise or selective synthesis.
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PEG8 Spacer: Enhances water solubility and reduces steric hindrance.
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High Purity: Reliable for sensitive and reproducible bioconjugation.
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Versatile: Compatible with aqueous and organic systems.
Applications:
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Bioconjugation: Conjugation of proteins, peptides, and biomolecules.
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Drug Delivery: PEGylation linker for improved solubility and pharmacokinetics.
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Surface Modification: Functionalization of nanoparticles, polymers, or biosensors.
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Material Science: PEGylation of polymers and advanced biomaterials.
Storage and Handling:
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Storage: Store at –20 °C, protected from moisture and light.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve reactivity.
This product combines a reactive amine, acid-labile ester protection, and PEG8 spacing, making it an especially useful tool for controlled conjugation and advanced research applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
