Amino-PEG3-t-butyl ester CAS:252881-74-6 is a versatile reagent that is commonly used in organic chemistry and biochemistry research. This reagent consists of a PEG (polyethylene glycol) chain with three ethylene glycol units, which is linked to an amino group and a t-butyl ester group. The t-butyl ester group provides a protecting group that can be removed under mild conditions, while the amino group can be used for further chemical modification or conjugation.
Amino-PEG3-t-butyl ester is commonly used in the synthesis of peptides, oligonucleotides, and other biomolecules. It can be used to introduce a PEG spacer between the biomolecule and other molecules, which can improve solubility, stability, and pharmacokinetic properties. In addition, the amino group can be used to conjugate the biomolecule with other molecules, such as fluorescent dyes, biotin, or nanoparticles.
Amino-PEG3-t-butyl ester is a white to off-white solid that is soluble in common organic solvents, such as DMSO, DMF, or THF. It should be stored at -20°C in a dry and dark place. Before use, it should be dissolved in anhydrous solvent and activated with a coupling agent, such as HATU or EDC, to improve the yield and purity of the reaction.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
