Amino-PEG3-CH2COOH
This product is a heterobifunctional PEG3 linker with a terminal primary amine and a carboxymethyl group. The PEG3 spacer provides hydrophilicity and flexibility, making it an especially versatile reagent for bioconjugation, drug delivery, and multifunctional material applications.
Key Features and Benefits:
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Amine Group: Couples efficiently with carboxyls, NHS esters, and other electrophiles.
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Carboxymethyl Group: Reacts with amines to form stable amide bonds.
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PEG3 Spacer: Balances solubility, flexibility, and compact chain length.
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High Purity: Ensures reproducibility in sensitive workflows.
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Dual Reactivity: Supports orthogonal and stepwise conjugation strategies.
Applications:
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Bioconjugation: Dual-reactive linker for proteins, peptides, and biomolecules.
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Drug Delivery: PEGylated linker enhances solubility, stability, and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
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Synthetic Chemistry: Serves as an intermediate in PEGylated scaffold design.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected environment.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve amine and acid integrity.
This product combines compact PEG spacing with amine and carboxyl reactivity, making it especially useful for bioconjugation, orthogonal synthesis, and advanced material engineering.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
