Alkyne-PEG-SSPy is a versatile linker for bioconjugation. It combines an alkyne group for click chemistry with azides and an SSPy (pyridyl disulfide) group for binding to thiols. The PEG4 spacer boosts solubility and flexibility, minimizing steric hindrance.
Key Features:
- Alkyne Group: Enables copper-catalyzed or copper-free click reactions with azides.
- SSPy Group: Reacts directly with thiol groups to form stable disulfide bonds.
- PEG4 Spacer: Enhances solubility and flexibility.
Applications:
- Protein and Peptide Conjugation: Links proteins or peptides to other molecules or surfaces.
- Antibody-Drug Conjugates (ADCs): Links drugs to antibodies for targeted therapy.
- Surface Functionalization: Modifies surfaces with specific functional groups for biosensors.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
