Alkyne-PEG4-SS-PEG4-alkyne is a versatile bifunctional linker, incorporating two alkyne groups, separated by two PEG4 (polyethylene glycol) units, and a central disulfide bond (SS). This unique combination offers enhanced solubility, increased flexibility, and a cleavable disulfide bridge, making it an ideal candidate for advanced bioconjugation techniques in pharmaceutical research.
In pharmaceutical research and development, Alkyne-PEG4-SS-PEG4-alkyne plays a critical role in the synthesis of targeted drug delivery systems and bioconjugates. Its disulfide bridge enables controlled release in a reducing environment, while the PEG4 spacers improve biocompatibility and pharmacokinetic properties. This linker is particularly useful in applications such as antibody-drug conjugates, targeted therapeutics, and bioorthogonal click chemistry, leading to innovative treatments with higher efficacy and fewer side effects.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
