AC-PEG-N3, MW 10K (Acrylate-PEG-Azide) consists of three essential components: acrylate, polyethylene glycol (PEG), and azide.
Acrylate is a vinyl group with a double bond that allows it to participate in a wide range of chemical reactions. In AC-PEG-N3, MW 10K, the acrylate group serves as the anchor point for attaching other functional groups to the PEG backbone. PEG, on the other hand, is a hydrophilic polymer widely used in drug delivery systems due to its ability to enhance the solubility, stability, and bioavailability of drugs. PEG also prevents drug degradation and clearance, thereby prolonging drug circulation time in the body.
Azide, a nitrogen-containing group, is a powerful functional group that undergoes a unique and selective reaction with alkyne or cyclooctyne groups, enabling site-specific bioconjugation with biomolecules. Azide groups are also useful for preparing clickable bioorthogonal probes, which enable the detection and visualization of biomolecules in living cells and tissues.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.