8-ArmPEG-Mal, MW 40K is a type of polyethylene glycol (PEG) derivative that contains eight arms, each terminated with a maleimide (Mal) functional group. The Mal group is a highly reactive moiety that can selectively react with thiol groups present in biomolecules.
PEG derivatives are commonly used in drug delivery systems due to their ability to improve solubility, stability, and pharmacokinetic properties of drugs. The eight-arm structure of 8-ArmPEG-Mal, MW 40K further enhances its properties, as it can create a more stable and biocompatible surface for drug delivery.
The Mal functional group allows for site-specific conjugation of 8-ArmPEG-Mal, MW 40K to proteins or peptides containing thiol groups, enabling the formation of bioconjugates. These bioconjugates can be used to target specific cells or tissues, improve drug efficacy, and reduce side effects.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.