6-Maleimido-1-Hexanal CAS:1076198-37-2 is a chemical compound used in biochemical research as a crosslinking agent. It contains a maleimide group, which can react with thiol groups on proteins to form a covalent bond, creating a stable and irreversible protein-protein or protein-peptide linkage. The compound also contains a six-carbon aldehyde chain, which allows it to be incorporated into polymers or other materials to create functionalized surfaces.
The maleimide group of 6-Maleimido-1-Hexanal has high selectivity for thiols, making it a useful tool for site-specific protein modification and crosslinking. The aldehyde group allows for further functionalization, such as conjugation to other molecules or immobilization onto surfaces for bioconjugation applications.
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