5-FAM-PEG4-Tetrazine is a novel, bifunctional molecular probe consisting of a 5-carboxyfluorescein (5-FAM) fluorophore, a polyethylene glycol spacer (PEG4), and a tetrazine moiety. This unique structure facilitates diverse applications in pharmaceutical research and development.
The 5-FAM fluorophore, known for its high photostability and bright green fluorescence, enables sensitive detection in various imaging and analytical techniques. The PEG4 linker imparts increased solubility and reduced steric hindrance, enhancing the probe’s compatibility with biomolecules. Lastly, the tetrazine group allows for bioorthogonal click chemistry reactions, particularly with strained alkenes and alkynes, such as trans-cyclooctenes or bicyclononynes. This feature enables rapid and selective labeling of biomolecules in living systems without interfering with native biochemical processes.
Common applications of 5-FAM-PEG4-Tetrazine include cell surface labeling, targeted drug delivery, and biomarker detection, contributing to the development of new therapeutics and diagnostics. Its versatile, multifunctional design establishes 5-FAM-PEG4-Tetrazine as a valuable tool in pharmaceutical research and development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
