5-Ethynyl Uridine (EU) CAS:69075-42-9 is a small molecule linker that contains an ethynyl group. The ethynyl group is a type of functional group that consists of a carbon-carbon triple bond, which is highly reactive and can undergo a variety of chemical reactions. In the context of EU, the ethynyl group can be used to covalently attach the molecule to other molecules or surfaces, allowing for the selective labeling and detection of RNA in cells.
EU is commonly used as a surrogate marker for newly synthesized RNA in various biological systems, as it can be incorporated into nascent RNA transcripts in vivo, which can then be detected and quantified using fluorescence-based techniques. This has led to the development of a range of imaging and detection methods for RNA, including fluorescence in situ hybridization (FISH), RNA-sequencing (RNA-seq), and Click-iT chemistry, which have become important tools for studying gene expression and RNA regulation in various biological processes.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.