4-Bromo-3-(hydroxymethyl)benzenesulfonamide
CAS Number: 60666-72-0
Chemical Information
- Molecular Formula: C7H8BrNO3S
- Molecular Weight: 266.11 g/mol
- Structure: Features a bromine atom at the 4-position, a hydroxymethyl group at the 3-position, and a sulfonamide group attached to the benzene ring.
Key Features
- Functional Groups:
- Bromine: Useful for halogen-based substitutions and cross-coupling reactions.
- Hydroxymethyl: Offers reactivity for further functionalization or hydrogen bonding.
- Sulfonamide: Increases hydrophilicity and bioactivity potential.
- Versatility:
- Can be used in organic synthesis for pharmaceuticals, agrochemicals, or material science applications.
Applications
- Pharmaceutical Research:
- Intermediate in the synthesis of bioactive molecules.
- Potential precursor for sulfonamide-based drugs.
- Organic Synthesis:
- Useful in cross-coupling reactions like Suzuki or Buchwald-Hartwig coupling due to the bromine group.
- Hydroxymethyl and sulfonamide groups allow for diverse functionalization pathways.
- Material Science:
- May contribute to the design of specialty polymers or other functional materials.
Storage and Handling
- Storage: Keep in a cool, dry place away from light and moisture.
- Safety: Handle with care; avoid inhalation and direct skin contact. Refer to the SDS for detailed safety instructions.
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