27-Alkyne Cholesterol
CAS: 1527467-07-7
Description:
27-Alkyne Cholesterol is a modified cholesterol with an alkyne group at the 27th position. This alkyne allows “click chemistry” with azide-functionalized molecules, enabling selective labeling and tracking in biological systems.
Key Features:
- Alkyne Group: Supports specific “click chemistry” with azide reagents in the presence of copper for precise molecular linking.
- Cholesterol Mimic: Recognized by enzymes like cholesterol oxidases and acyl transferases in species such as yeast, rats, and humans, producing expected metabolites.
- Detection Versatility: Works with fluorescence microscopy, mass spectrometry, and other techniques to trace cholesterol in cell structures like the Golgi, ER, and mitochondria.
Applications:
- Cellular Tracking: Enables high-resolution visualization of cholesterol distribution in various cell compartments.
- Cholesterol Research: Useful for studying cholesterol metabolism, lipid transport, and enzyme interactions.
- Bioconjugation: Allows attachment of drugs or probes to cholesterol for targeted delivery.
- Advanced Detection: Ideal for mass spectrometry and click chemistry in lipidomics and cell biology.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
