2-Amino-1,3-bis(t-butoxycarbonylethoxy)propane
This product is a Boc-protected diamino ether derivative with a central propane backbone. The terminal tert-butoxycarbonyl (Boc)-protected groups provide stability during synthesis, while the free amine allows for further functionalization in peptide, linker, and polymer chemistry.
Key Features and Benefits
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Protected Diamino Structure: Contains two Boc-protected ethoxy side chains for orthogonal deprotection.
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Free Amine Handle: Enables conjugation via amide, carbamate, or urea bond formation.
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Stable Boc Groups: Protect amines during multistep synthesis under mild acidic removal conditions.
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Versatile Building Block: Suitable for linker, dendrimer, and polymer precursor synthesis.
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High Purity: Manufactured and purified to ≥95% for consistent synthetic performance.
Applications
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Peptide Chemistry: Serves as a protected diamino building block in custom peptide synthesis.
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Bioconjugation: Facilitates creation of multifunctional linkers for biomolecule coupling.
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Drug Delivery Systems: Used as a structural spacer or solubilizing unit in prodrug or nanoparticle design.
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Polymer and Dendrimer Synthesis: Acts as a precursor for advanced polymer scaffolds.
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Medicinal Chemistry: Supports synthesis of protected intermediates in drug discovery workflows.
Storage and Handling
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Storage: Store at –20 °C in a sealed, desiccated container.
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Handling: Avoid exposure to moisture and strong acids; deprotect Boc groups under mild acidic conditions when needed.
This product combines a free amine with two Boc-protected groups, specifically offering a versatile intermediate for linker design, bioconjugation, and advanced chemical synthesis.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
