16:0 PEG PE, MW 2K CAS: 474922-84-4 is a high-quality, biocompatible lipid-based reagent with a molecular weight of 2,000 Daltons. It consists of a phospholipid moiety (dipalmitoyl phosphatidylethanolamine, 16:0 PE) conjugated to a hydrophilic methoxy(polyethylene glycol) (mPEG) chain.
The amphiphilic nature of 16:0 PEG PE permits the formation of stable micelles, liposomes, and other nanostructures that encapsulate hydrophobic or hydrophilic drugs, increasing their solubility, bioavailability, and circulation time. The PEGylation of the phospholipid imparts stealth properties, reducing immunogenicity and nonspecific interactions with biological components.
Applications of 16:0 PEG PE include targeted drug delivery, gene therapy, and diagnostics. Its use in the development of liposomal and nanoparticle-based formulations has proven particularly beneficial for anticancer and anti-inflammatory therapeutics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
