DOPS (1,2-Dioctadecenoyl-sn-glycero-3-phosphoserine), (DOPS Lipid) CAS:90693-88-2, also known as 1,2-Dioctadecenoyl-sn-glycero-3-Phospho-L-serine, is an anionic phospholipid commonly used in liposome formation and membrane research. It features oleic acid tails (18:1) and a head group containing both a carboxylic acid (COOH) and amine (NH2) group, making it a highly flexible and functional lipid.
Key Features:
- Anionic Properties: The negatively charged phospho-L-serine head group gives DOPS its unique ability to form negatively charged liposomes or artificial membranes, which are commonly used in biological and pharmaceutical research.
- Flexible Oleic Acid Tails: The 18:1 oleic acid chains provide fluidity to lipid bilayers, mimicking natural cell membranes for more accurate research results.
Applications:
- Liposome Formation: DOPS is widely used to create liposomes for drug delivery and vaccine development, enhancing the stability and functionality of these delivery systems.
- Membrane Research: It plays a crucial role in studying protein-lipid interactions, making it an essential component in membrane-related studies and artificial membrane models.
- Lipid Mixing: DOPS is also used in the preparation of lipid-mixing vesicles, helping researchers study lipid behavior and bilayer formation in controlled settings.
DOPS is available in reagent grade for research purposes and can be customized for GMP-grade applications upon request. Its versatility in creating membranes, liposomes, and other lipid-based systems makes it indispensable for biotechnology and pharmaceutical applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
