Biotin-PEG2-Hydrazide
This product is a high-purity biotinylation reagent featuring a terminal hydrazide group linked through a short PEG2 spacer. This design specifically allows efficient labeling of aldehyde- or ketone-containing biomolecules, while maintaining biotin’s strong affinity for streptavidin and avidin.
Key Features and Benefits
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Biotin Moiety – Provides high-affinity, specific binding to streptavidin and avidin systems.
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Hydrazide Group – Reacts selectively with aldehydes and ketones for stable hydrazone bond formation.
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PEG2 Spacer – Enhances solubility and reduces steric hindrance in conjugation reactions.
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High Purity – Ensures reliable performance in bioconjugation and analytical applications.
Applications
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Biotinylation of oxidized glycans, proteins, or antibodies
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Conjugation to aldehyde-functionalized biomaterials or surfaces
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Probe development for diagnostics and biosensor platforms
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Labeling for imaging, assay, and drug delivery studies
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents (e.g., DMF, DMSO). Avoid repeated freeze–thaw cycles.
This product is a biotinylation linker with a hydrazide group on a PEG2 spacer, enabling efficient conjugation with aldehyde- or ketone-containing molecules while improving solubility and reducing steric hindrance.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
