Biotin-NH-CH2CH2-S-S-Pyr CAS:112247-65-1 is a biotinylated reagent widely used in bioconjugation and protein modification applications. The reagent consists of a biotin group, a linker consisting of a two-carbon chain with a disulfide bond, and a pyridyl disulfide group at the end of the linker.
The biotin group, a vitamin H derivative, is widely used in bioconjugation applications because of its strong and selective binding to avidin or streptavidin. The linker is useful in introducing a spacer between the biotin and the target molecule, which can improve the accessibility and binding efficiency of the biotin group. The pyridyl disulfide group can selectively react with thiol-containing biomolecules, such as cysteine residues, to form a disulfide bond.
Biotin-NH-CH2CH2-S-S-Pyr is commonly used in the modification of proteins, peptides, and other biomolecules. It can be used to attach biotin to target molecules, which can be used for detection, purification, or immobilization purposes. The use of a linker can also improve the solubility and stability of the target molecule.
Biotin-NH-CH2CH2-S-S-Pyr is a white to off-white solid that is soluble in a range of organic solvents, such as DMF, DMSO, or ethanol. It should be stored at -20°C in a dry and dark place to maintain its stability and quality.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
