Amino-PEG4-t-butyl ester CAS:581065-95-4 is a common reagent used in organic chemistry and biochemistry research. It is a versatile molecule consisting of a polyethylene glycol (PEG) chain with four ethylene glycol units, linked to an amino group and a t-butyl ester group. The t-butyl ester group provides a protecting group that can be easily removed under mild conditions, while the amino group can be used for further chemical modification or conjugation.
Amino-PEG4-t-butyl ester is frequently used in the synthesis of peptides, oligonucleotides, and other biomolecules. It is particularly useful for introducing a PEG spacer between the biomolecule and other molecules, which can improve solubility, stability, and pharmacokinetic properties. In addition, the amino group can be used to attach the biomolecule to other molecules, such as fluorescent dyes, biotin, or nanoparticles.
Amino-PEG4-t-butyl ester is a white to off-white solid that is soluble in a range of common organic solvents, such as DMSO, DMF, or THF. It should be stored at -20°C in a dry and dark place. Before use, it should be dissolved in anhydrous solvent and activated with a coupling agent, such as HATU or EDC, to improve the yield and purity of the reaction.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
