DMT-2′-O-Methyl-rC(tac) Phosphoramidite (CAS: 179486-26-1) is a key reagent for RNA oligonucleotide synthesis. The 2′-O-methyl modification provides enhanced stability and resistance to nuclease degradation. The DMT group simplifies synthesis monitoring, while the (tac) group protects the cytidine nucleobase during the process.
Key Features:
- 2′-O-Methyl Modification: Increases stability and protects RNA from enzymatic degradation. Ideal for biological and therapeutic applications.
- DMT Group: Enables easy monitoring and purification during synthesis, offering more control.
- tac Protection: Ensures efficient coupling and reduces side reactions.
Applications:
- RNA Oligonucleotide Synthesis: Perfect for creating stable RNA strands for research, diagnostics, and therapeutics.
- Therapeutics: Highly resistant to degradation, making it ideal for RNA-based drugs and antisense oligonucleotides.
- Diagnostic Tools: Ideal for RNA probes used in molecular diagnostics, where stability and precision are key.
Benefits:
- Enhanced Stability: The 2′-O-methyl modification increases resistance to degradation, making RNA more durable in biological settings.
- Precise Synthesis: The DMT group makes it easier to track and purify oligonucleotides during synthesis.
- High-Purity RNA: The tac protection ensures clean synthesis with minimal side reactions, producing high-quality RNA.
DMT-2′-O-Methyl-rC(tac) Phosphoramidite (CAS: 179486-26-1) offers the stability and precision needed for RNA synthesis, making it perfect for research and therapeutic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
