MMT-Hexylaminolinker Phosphoramidite, CAS 114616-27-2, acts as a cleavable linker for oligonucleotide synthesis. It includes a hexylamino linker protected by a monomethoxytrityl (MMT) group. This design allows for controlled deprotection and easy post-synthesis modifications. Researchers often use it to synthesize oligonucleotide gapmers or other nucleic acid molecules, where a functional amino group is needed for bioconjugation and labeling.
Key Features
- Cleavable Linker: Enables selective deprotection for controlled modifications.
- MMT Protection: Supports efficient deprotection of the amino linker for further conjugation.
- Hexylamino Linker: Provides a flexible spacer for attaching various molecules, increasing oligonucleotide versatility.
- Phosphoramidite Chemistry: Easily integrates with standard DNA/RNA synthesis protocols.
Applications
- Oligonucleotide Synthesis: Ideal for creating oligonucleotide gapmers and other modified nucleic acids.
- Bioconjugation: Attaches labels, dyes, or other molecules to oligonucleotides for further functionalization.
- Molecular Probes: Develops modified probes for detecting specific nucleic acid targets.
MMT-Hexylaminolinker Phosphoramidite offers a versatile and efficient approach to nucleic acid synthesis, making it ideal for advanced research and therapeutic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
