DMT-dT Phosphoramidite (also known as 5′-O-DMT-Thymidine-CE Phosphoramidite, CAS 98796-51-1) is a widely used thymidine phosphoramidite for DNA oligonucleotide synthesis. It features a 5′-O-DMT (dimethoxytrityl) protecting group, ensuring controlled and efficient assembly of DNA sequences during solid-phase synthesis.
Key Features:
- CAS Number: 98796-51-1
- Other Names: 5′-O-DMT-Thymidine-CE Phosphoramidite
- Chemical Structure: Thymidine with a 5′-O-DMT protecting group
- Function: Building block for DNA oligonucleotide synthesis
- Protection Groups: 5′-O-DMT group for the 5′ hydroxyl of thymidine
- Applications:
- Used in solid-phase synthesis of DNA for research, diagnostics, and therapeutic applications
- Common in creating custom DNA sequences for genetic studies
DMT-dT Phosphoramidite allows precise and controlled thymidine incorporation into oligonucleotides, making it essential for efficient DNA synthesis in both research and applied genetic sciences.
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