Product Overview: Fmoc-Asp(biotinyl-PEG)-OH (CAS: 2241747-15-7)
Fmoc-Asp(biotinyl-PEG)-OH is a versatile biotinylation reagent featuring a terminal Fmoc group. It enables efficient biotin tagging in peptide synthesis and bioconjugation processes. The PEG chain enhances solubility, while the biotin allows for easy detection in various assays.
Key Features:
- Fmoc Group: Protects the amine during synthesis and is easily removed under basic conditions.
- Biotinylated PEG: Enhances solubility and reduces steric hindrance. The biotin tag binds strongly with streptavidin or avidin.
- Aspartic Acid Core: Acts as a linker to incorporate biotin into peptides during synthesis.
Applications:
- Biotinylation: Efficiently reacts with amines using activators like EDC or HATU. It’s ideal for bioconjugation and labeling.
- Peptide Synthesis: Used in solid-phase synthesis for creating biotinylated peptides.
- Detection: Biotin-tagged peptides and proteins bind with streptavidin or avidin, making them easy to detect.
Benefits:
- Efficient Amine Reaction: Activates with EDC or HATU for quick and targeted amine reactions.
- Simple Deprotection: The Fmoc group is easily removed under basic conditions for further modifications.
- Enhanced Solubility: The PEG chain ensures smooth reactions even in complex environments.
Fmoc-Asp(biotinyl-PEG)-OH (CAS: 2241747-15-7) is an ideal choice for biotinylating peptides and proteins, ensuring effective labeling and detection for various research applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.