Acrylate-PEG-Maleimide (ACRL-PEG-MAL), MW 1K is a heterobifunctional PEG reagent with an acrylate on one end and a maleimide on the other. Can be used to prepare hydrogels. Pegylation can increase the solubility and stability and reduce immunogenicity of peptides and proteins.
The maleimide group in Acrylate-PEG-Maleimide has been exploited for the site-specific conjugation of biomolecules. The thiol-maleimide reaction is a selective and efficient way to attach thiol-containing molecules, such as proteins and peptides, to the PEG chain, resulting in bioconjugates with improved stability and pharmacokinetics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
