Cholesterol-PEG-Amine(CLS-PEG-NH2), MW 3.4K, is a unique bifunctional reagent designed to facilitate drug delivery research and bioconjugation applications in pharmaceutical R&D. This versatile compound features cholesterol, polyethylene glycol (PEG), and amine functional groups.
The cholesterol moiety provides lipophilic properties, allowing for enhanced membrane interactions and incorporation into lipid-based drug delivery systems, such as liposomes and lipid nanoparticles. The hydrophilic PEG chain offers stealth properties, improving stability, and minimizing immune recognition. The terminal amine group enables efficient conjugation to a variety of biomolecules, including proteins, peptides, and nucleic acids.
Cholesterol-PEG-Amine, MW 3.4K has demonstrated immense potential in the development of targeted drug delivery systems and as a bioconjugation reagent. Applications include improving pharmacokinetic profiles, enhancing solubility, and increasing circulation time of therapeutic agents. Furthermore, it serves as an ideal linker for constructing antibody-drug conjugates and other targeted therapies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
