The E3 ligase Ligand 1a is a VH032 derivative used in PROTAC conjugation reactions for the synthesis of ARV-771, a BET PROTAC degrader. It can also hijack VHL as an E3 ubiquitin ligase component.
E3 Ligase ligand 1a (also known as E3L1a) is a small molecule that binds to the E3 ubiquitin ligase protein complex, which is responsible for tagging proteins for degradation. It is an inhibitor of the E3 ubiquitin ligase complex and is used to study the role of the E3 ubiquitin ligase complex in protein degradation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
