MZ1 is a PROTAC compound selective for proteasomal degradation of bromodomain-containing protein 4 (BRD4) in HeLa cells. MZ1 contains JQ-1, which binds bromo and extra-terminal (BET) proteins linked to ligands of the E3 ubiquitin ligase VHL.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.