t-Boc-Aminooxy-PEG3-S-Ac CAS:2055040-71-4, also known as tert-butyloxycarbonyl-aminooxy-polyethylene glycol-3-thioacetate, is a unique, bifunctional PEGylation reagent. With a t-Boc-protected aminooxy moiety and a thiol-reactive acetyl group, it facilitates site-specific conjugation to biomolecules, enhancing solubility, stability, and pharmacokinetics.
In pharmaceutical research and development, t-Boc-Aminooxy-PEG3-S-Ac plays a vital role in the synthesis of bioconjugates, such as antibody-drug conjugates (ADCs) and PEGylated peptides or proteins. By enabling selective conjugation and deprotection strategies, this reagent significantly improves drug efficacy and safety, reducing immunogenicity and off-target effects, ultimately expediting the discovery and development of innovative therapeutics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.