Bis-PEG21-PFP ester is a bifunctional polyethylene glycol (PEG) derivative known for its high hydrophilicity and biocompatibility. As a versatile crosslinking agent, it features two activated pentafluorophenyl (PFP) ester groups at each end, facilitating efficient conjugation with amine-containing molecules.
Bis-PEG21-PFP ester is extensively employed in the synthesis of PEGylated bioconjugates, where it enhances the pharmacokinetics, solubility, and stability of therapeutic proteins and peptides. Its application in drug delivery systems, including targeted nanoparticles and hydrogels, has shown potential to improve controlled release and reduce immunogenicity of biopharmaceuticals. Additionally, Bis-PEG21-PFP ester’s use in surface modification of medical devices or implants has been pivotal in promoting biocompatibility and reducing host response.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
