t-Boc-N-amido-PEG16-NHS ester is a high purity, bifunctional PEGylation reagent with a tertiary-butoxycarbonyl (t-Boc) protected amine group and an N-hydroxysuccinimide (NHS) ester group. It exhibits excellent stability and reactivity, allowing for controlled conjugation and deprotection of amine-bearing molecules in a diverse range of applications.
In pharmaceutical research and development, t-Boc-N-amido-PEG16-NHS ester is utilized as a versatile linker in the synthesis of bioconjugates, such as antibody-drug conjugates, PEGylated proteins, and drug delivery systems. Its PEGylation properties enhance solubility, reduce immunogenicity, and increase the half-life of therapeutic molecules, leading to improved pharmacokinetic profiles and overall efficacy of the conjugated drugs.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
