Azide-PEG8-Tos CAS:857892-34-3 produced by Axispharm is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a non-cleavable 8-unit PEG ADC linker for the synthesis of antibody-drug conjugates (ADCs). The azide group is reacted with terminal alkyne and cyclooctyne derivatives via click chemistry, and the tosyl group can be replaced by a nucleophile for bioconjugation and pegylation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.