Azide-PEG2-Tos CAS:182347-24-6 from Axispharm is a heterobifunctional PEG linker containing an azide group and a tosyl group. It is a non-cleavable 2-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The azide group is reacted with terminal alkyne and cyclooctyne derivatives via click chemistry, and the tosyl group can be replaced by a nucleophile for bioconjugation and pegylation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.