Biotin-PEG-Biotin, MW 3.4K is a high-quality, bifunctional polyethylene glycol (PEG) linker that plays a pivotal role in pharmaceutical research and development. PEGylation with biotin imparts exceptional solubility, stability, and reduced immunogenicity to biomolecules, enhancing their therapeutic potential.
The Biotin-PEG-Biotin, MW 3.4K linker consists of two biotin moieties, each conjugated to a hydrophilic PEG polymer. Biotin is a small, biocompatible molecule that exhibits strong and specific binding to streptavidin or avidin, enabling affinity-based purification and detection methods. The PEG spacer imparts flexibility and lowers steric hindrance, facilitating optimal binding and interaction between linked biomolecules.
This versatile reagent finds application in diverse areas, including drug delivery, protein conjugation, and targeted therapy. It serves as a powerful tool for conjugating biotinylated biomolecules such as antibodies, proteins, and nucleic acids, and for constructing targeted drug delivery systems.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
