TCO-benzoic acid CAS:1233349-54-6 is a type of chemical compound that contains several functional groups, including a carboxylic acid group and a tetrazine group. The carboxylic acid group is an important functional group in organic chemistry, as it is involved in many chemical reactions, including esterification and amidation. The tetrazine group is a heterocyclic ring structure that has been widely used in bioconjugation and drug discovery, as it can react with strained alkenes or alkynes to form stable and bioorthogonal bonds.
In bioconjugation, TCO-benzoic acid can be used as a linker molecule to attach proteins or peptides to surfaces, nanoparticles, or other molecules that contain tetrazine groups. The TCO group in TCO-benzoic acid can react with tetrazine groups through a cycloaddition reaction known as the tetrazine ligation reaction. This reaction is highly efficient and selective, and can be used for a variety of biological applications, including protein labeling, drug delivery, and imaging.
TCO-benzoic acid represents an important tool in the field of bioconjugation and drug discovery, allowing for the creation of targeted drug delivery systems and imaging agents. The combination of carboxylic acid and tetrazine functional groups in TCO-benzoic acid provides a versatile and efficient platform for the conjugation of proteins and other biomolecules, enabling researchers to develop new and innovative therapies for a variety of diseases.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
