Thalidomide-O-amido-propoxy-PEG2-C3-NHBoc CAS:1799711-31-1 is a small molecule drug that is used in the treatment of certain types of cancer and inflammatory diseases. It is composed of several functional groups, including a thalidomide group, a PEG spacer, an amido-propoxy group, and a NHBoc group.
Thalidomide is a type of immunomodulatory drug that has been shown to be effective in treating certain types of cancer, such as multiple myeloma and myelodysplastic syndromes, as well as inflammatory diseases such as rheumatoid arthritis and Crohn’s disease. The PEG spacer in Thalidomide-O-amido-propoxy-PEG2-C3-NHBoc is used to improve the solubility and stability of the drug in solution, allowing it to be more easily administered to patients. The amido-propoxy group is important for enhancing the chemical stability and bioavailability of the compound. The NHBoc group is used to protect the amine functional group in the compound during synthesis, allowing for more precise control over the reaction conditions.
In terms of its mechanism of action, Thalidomide-O-amido-propoxy-PEG2-C3-NHBoc works by modulating the activity of certain immune cells in the body, particularly T cells and natural killer cells. By enhancing the activity of these cells, Thalidomide-O-amido-propoxy-PEG2-C3-NHBoc can help to boost the body’s immune response to cancer cells and reduce inflammation, leading to improved outcomes for patients with cancer and inflammatory diseases.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.