(2-methylcyclopropenyl)methyl 4-nitrophenyl carbonate

• Carbonate Group: Attaches to proteins and peptides through nucleophilic substitution, forming stable bonds with primary amines.
• Cyclopropene Group: Enables selective labeling through copper-catalyzed azide-alkyne cycloaddition (CuAAC) for precise biomolecule detection.

Key Applications

1. Bioconjugation: Enables stable attachment to retain each component’s properties.
2. Protein and Peptide Modification: Easily attaches to primary amines, forming strong bonds.
3. Bioorthogonal Labeling: Supports selective biomolecule detection in complex systems.
4. Targeted Drug Delivery: Enhances targeting, efficacy, and reduces toxicity.
5. Pharmacokinetics Improvement: Increases drug stability and circulation time.
6. Targeted Therapeutics: Enables precise delivery, reducing side effects and increasing specificity.

(2-methylcyclopropenyl)methyl 4-nitrophenyl carbonate supports drug discovery by helping researchers create safer, more effective therapies.