PC Biotin-NHS ester is a small molecule linker that is commonly used in bioconjugation and protein labeling applications. It is a biotin derivative that contains a succinimidyl ester functional group, which allows it to react with primary amines on the surface of proteins or other biomolecules.
The succinimidyl ester group in PC Biotin-NHS ester can undergo nucleophilic attack by the primary amines on lysine residues or the N-terminus of proteins, forming a stable amide bond. This reaction is highly efficient and specific, resulting in site-specific modification of the biomolecule with the biotin tag.
Biotin is a small molecule that binds tightly to avidin and streptavidin proteins, making it a popular choice for protein labeling and purification. The addition of a biotin tag to a protein or other biomolecule can enable sensitive detection, quantification, and purification of the molecule using streptavidin-coated surfaces or beads.
PC Biotin-NHS ester is a small molecule linker that can be used to conjugate a biotin tag to proteins or other biomolecules, enabling sensitive detection, quantification, and purification. Its use in bioconjugation and protein labeling has become widespread in biological and medical research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
