Diketone-PEG4-PFP ester CAS:2353409-84-2 is a multifunctional crosslinking reagent, designed to facilitate conjugation and bioconjugation processes in pharmaceutical research and development. The ester is composed of two functional groups: diketone and pentafluorophenyl (PFP). The diketone group enables selective binding with primary amine groups, while the PFP ester reacts with amines, thiols, and hydroxyl groups, providing flexibility for various conjugation applications.
Diketone-PEG4-PFP ester’s polyethylene glycol (PEG) spacer imparts increased solubility and stability, reducing aggregation and non-specific binding. This hydrophilic linker is particularly useful in the development of targeted drug delivery systems, bioconjugate vaccines, and diagnostic agents.
In pharmaceutical , the diketone-PEG4-PFP ester has gained prominence for its versatility and biocompatibility. Its applications include protein and peptide labeling, development of antibody-drug conjugates, and immobilization of biomolecules on solid surfaces. By facilitating selective conjugation, it streamlines the development of advanced therapeutic and diagnostic modalities.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
