Hydroxy-PEG3-SS-PEG3-alcohol
This product is a symmetric PEG linker featuring terminal hydroxyl groups separated by a reducible disulfide bond and PEG3 spacers, specifically offering hydrophilic, cleavable, and versatile functionality for bioconjugation and drug delivery applications.
Key Features and Benefits
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Terminal Hydroxyls: Enable further functionalization or derivatization.
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Disulfide Bond: Provides cleavable linkage under reducing conditions.
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PEG3 Spacers: Enhance solubility, flexibility, and biocompatibility.
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Symmetric Design: Facilitates balanced modification strategies.
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High Purity: Manufactured to ≥95% for reproducible results.
Applications
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Bioconjugation: Links biomolecules with reducible PEG spacers.
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Drug Delivery: Enables controlled release via disulfide cleavage.
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Surface Modification: Functionalizes nanoparticles, hydrogels, and polymers.
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Crosslinking: Creates reversible linkages in biomaterials.
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Redox-Sensitive Studies: Useful in intracellular release research.
Storage and Handling
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Storage: Store at –20 °C in a sealed, desiccated container.
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Handling: Prepare fresh solutions; disulfides are sensitive to reducing agents.
This product combines terminal hydroxyl reactivity with a cleavable disulfide bridge, making it an especially valuable tool for redox-responsive bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
