Dde Biotin-PEG4-DBCO CAS: 1807512-43-1 contains a biotin functional group, a PEG4 linker, and a dibenzocyclooctyne (DBCO) group. The biotin group is known for its high affinity for avidin or streptavidin.
Dde Biotin-PEG4-DBCO is useful for introducing a biotin moiety to alkyne-containing biomolecules using Click Chemistry. The hydrophilic spacer arm improves the solubility of the labeled molecules in aqueous media. Dde protecting group allows efficient release of captured biotinylated molecules from streptavidin/avidin under mild conditions with hydrazine.
Dde Biotin-PEG4-DBCO has been extensively used in bioconjugation and labeling applications. Its unique chemical properties allow for the covalent attachment of biotinylated molecules, such as proteins, peptides, and nucleic acids, to Dde Biotin-PEG4-DBCO via a DBCO-azide click reaction.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
