Azido-PEG1-Val-Cit-OH is a cleavable linker for targeted drug delivery and bioconjugation. Its azide group supports click chemistry, while the PEG1 spacer improves solubility. The Val-Cit dipeptide enables enzyme-specific cleavage by cathepsin B, ensuring precise drug release inside target cells.
Key Features:
- Functional Groups: Azide for click chemistry, PEG1 for solubility, and Val-Cit for enzyme-triggered cleavage.
- Molecular Formula: C₁₆H₂₉N₇O₆
- Molecular Weight: 415.44 g/mol
- Purity: ≥95%
Applications:
- Antibody-Drug Conjugates (ADCs): Releases drugs upon cathepsin B cleavage for targeted cancer therapy.
- Click Chemistry: Reacts efficiently with alkyne-containing molecules.
- Bioconjugation: Links biomolecules while enhancing water solubility and reducing steric hindrance.
This linker supports precision therapeutics by enabling controlled drug release and efficient molecular assembly.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
