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PEG & ADC

Home » Archive by Category "PEG & ADC"
25 Sep
PEG & ADC

What Is Ionizable Lipids?

  • September 26, 2023
  • By axispharm
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Ionizable lipids are a category of lipid molecules that maintain a neutral charge at normal physiological pH but ...

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25 Sep
PEG & ADC

What are Cationic Lipids?

  • September 26, 2023
  • By axispharm
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Cationic lipids belong to a group of lipid molecules characterized by a permanently positively charged head group...

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02 Jul
PEG & ADC

Agilent 1290 Infinity UPLC/ AB Sciex 5500 Qtrap Mass Spectrometer

  • July 28, 2023
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The 1290 Infinity...

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28 Jun
PEG & ADC

Polyethylene Glycol Classification

  • June 28, 2023
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Polyethylene Glycol can be categorized into different types based on factors such as synthesis geometry, molecul...

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20 Jun
PEG & ADC

Solid Lipid Nanoparticles (SLNs)

  • June 20, 2023
  • By axispharm
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Solid lipid nanoparticles (SLNs) have emerged as a promising drug delivery system due to their various advantage...

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19 Jun
PEG & ADC

In Vitro vs In Vivo Studies of Polyethylene Glycol (PEG) Linkers

  • July 2, 2023
  • By axispharm
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Polyethylene glycol (PEG) molecules have been used extensively as linkers in drug development, mainly due to the...

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22 May
PEG & ADC

Why Human epidermal growth factor receptor 2 (HER2) is an attractive target for ADC

  • May 25, 2023
  • By axispharm
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HER2 (Human Epidermal Growth Factor Receptor 2) is a protein that ...

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10 Feb
PEG & ADC

What is the difference between ADC linker and PEG linker?

  • June 4, 2023
  • By axispharm
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Linkers are molecules used to connect two different molecules together to form a larger, more complex structure. They are used in many ...

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09 Feb
PEG & ADC

Application of PEG Linker

  • July 21, 2023
  • By axispharm
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A PEG (polyethylene glycol) linker is a chemical compound that is used to connect two or more molecules together. PEG is a water-solubl...

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24 Nov
PEG & ADC

Antibody-drug conjugates(ADCs) list Approved by FDA(2000-2023)

  • August 29, 2023
  • By axispharm
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Antibody-drug conjugates(ADCs) are use specific linkers to connect antibodies and small molecule cytotoxic drugs, and their main compon...

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14 Nov
PEG & ADC

What is biotinylation?

  • November 15, 2022
  • By axispharm
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Biotinylation refers to the process of covalently attaching biotin to proteins, nucleic acids or other molecules. Due to the small mole...

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11 Nov
PEG & ADC

What are the ingredients of a COVID-19 vaccine?

  • November 11, 2022
  • By axispharm
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What is an mRNA vaccine? Like other types of vaccines, mRNA vaccines work by activating our own immune response, so that our bodies pro...

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10 Nov
PEG & ADC

The Importance of Polyethylene Glycol (PEG) to the Pharmaceutical Industry

  • December 13, 2022
  • By axispharm
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Polyethylene glycol (PEG) is a safe, inactive, and nontoxic polymer that is commonly used for molecular modification. Therapeutic benef...

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09 Nov
PEG & ADC

Technical characteristics of PROTAC technology in drug research and development

  • November 9, 2022
  • By 乐无琼
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Most of the drugs currently in clinical use are based on small molecules and use an "occupancy-driven" mode of action to inhibit the fu...

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08 Nov
PEG & ADC

What is SPDP Crosslinker?

  • November 8, 2022
  • By axispharm
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SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive grou...

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07 Nov
PEG & ADC

What is SPAAC?

  • October 30, 2023
  • By axispharm
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The 2022 Nobel Prize in Chemistry has been awarded to American chemist Carolyn Bertozzi, Danish chemist Morten Meldal and American chem...

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05 Nov
PEG & ADC

Difference Between Polymer PEG (Polydisperse PEG) and Monodisperse PEG

  • July 21, 2023
  • By axispharm
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The polymer PEG is a polyethylene glycol (PEG) polymer, a polyether compound derived from petroleum that has many applications ranging ...

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04 Nov
PEG & ADC

What is polyethylene glycol (PEG) modification?

  • August 29, 2023
  • By axispharm
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Polyethylene glycol (PEG) modification is a polyethylene glycol with functional groups, which is mainly used for protein drug modificat...

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28 Oct
PEG & ADC

What are ADC Linkers?

  • August 29, 2023
  • By axispharm
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Antibody-drug conjugates (ADCs) are the most popular chemoimmunotherapy agents in recent years. ADCs can enhance the ability to target ...

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18 Oct
PEG & ADC

The list of PEGylated drugs approved by FDA Up to 2022

  • October 18, 2022
  • By axispharm
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Polyethylene glycol (PEG) is a polymer material that is widely used for covalent modification of biopolymers such as proteins and pepti...

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07 Oct
PEG & ADC

The role of CYP450 in drug metabolism

  • October 7, 2022
  • By axispharm
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Drugs entering the body will be catalyzed into polar molecules under the action of a series of enzymes, and the process of exerting dru...

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30 Sep
PEG & ADC

What is polyethylene?

  • September 30, 2022
  • By axispharm
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Polyethylene (PE) is a thermoplastic resin obtained by polymerizing ethylene. In industry, copolymers of ethylene with small amounts of...

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29 Sep
PEG & ADC

What are lipids?

  • June 8, 2023
  • By axispharm
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Lipids are a class of non-polar organic solvents that are insoluble in water but easily soluble in fatty solvents. and important organi...

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28 Sep
PEG & ADC

What are phospholipids?

  • June 13, 2023
  • By axispharm
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Phospholipids are lipids containing phosphoric acid and belong to complex lipids. Phospholipids are the main components of biological m...

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27 Sep
PEG & ADC

GLP-1 receptor agonist Drug list and mechanism of action

  • September 27, 2022
  • By axispharm
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Glucagon-like peptide-1 receptor agonists, namely GLP-1 receptor agonists, are a class of drugs for the treatment of type 2 diabetes. T...

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08 Jul
PEG & ADC

What is the fluorescent dye?

  • October 7, 2023
  • By axispharm
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Fluorescent dyes refer to substances that absorb a light wave of a certain wavelength and emit another light wave with a wavelength gre...

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07 Nov
PEG & ADC

Log D Measurement

  • November 7, 2021
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Lipophilicity refers to the tendency of a compound to partition between a lipophilic organic phase and a pol...

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28 Aug
PEG & ADC

Stem cells successfully repair refractory type 1 diabetes

  • August 28, 2021
  • By axispharm
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With the improvement of people's living standard, the incidence of diabetes is increasing day by day. This poses ...

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27 Aug
PEG & ADC

ADC drug for urothelial carcinoma( effective rate 81.6%)

  • June 28, 2022
  • By axispharm
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Urothelial carcinoma (UC) is a common type of bladder cancer, accounting for approximately 90% of all bladder can...

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18 Aug
PEG & ADC

Can changing your diet help fight cancer?

  • August 18, 2021
  • By axispharm
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An article published on «Nature» stated that diet can adjust insulin levels and improve the anticancer effect of ...

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14 Aug
PEG & ADC

Can proteomic technology be used for cancer clinical research?

  • August 14, 2021
  • By axispharm
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Analysis of the tumor gene portfolio transcriptome is now a tool for novel biomarkers, but changes in proteome ex...

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13 Aug
PEG & ADC

Scientists Develop Magical Nanoparticles For Treat The Brain Cancer

  • August 13, 2021
  • By axispharm
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In recent years, due to the development of medical technology, scientists continue to explore new ways to treat c...

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07 Aug
PEG & ADC

Application of lipidomics in the diagnosis and treatment of tumors

  • August 7, 2021
  • By axispharm
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Lipids have a number of key biological functions in cancer. There are characteristic changes in lipid metabolism ...

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05 Aug
PEG & ADC

Focus on exosome applications and challenges

  • August 5, 2021
  • By axispharm
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Currently, the main application directions of exosomes include as drug delivery carriers; Immune activation and i...

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31 Jul
PEG & ADC

Omics applications of biomarkers (proteomics/metabolomics)

  • July 31, 2021
  • By axispharm
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The biomarker is a kind of characteristic biochemical index that can be evaluated objectively, and the biological...

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30 Jul
PEG & ADC

Proteomic Technology – Tumor Marker “Radar”

  • July 30, 2021
  • By axispharm
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Proteomics can analyze and identify the changes of protein molecules in tumor cells, providing valuable informati...

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24 Jul
PEG & ADC

Cancer Driver Genes Affect Cell Surface Proteins And Glycoprotein Groups

  • July 24, 2021
  • By axispharm
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The cell surface proteome is the interface where normal cells and cancer cells contact the extracellular space an...

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22 Jul
PEG & ADC

Drug Development: Virtual Screening/Molecular Docking/QSAR

  • July 22, 2021
  • By axispharm
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Structure-based drug design (SBDD) and ligand-based drug design (LBDD) are two basic methods of computer-aided dr...

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13 Jul
PEG & ADC

What is metabolomics?

  • July 13, 2021
  • By axispharm
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The metabolome is downstream of the gene regulatory network and protein action network and provides terminal info...

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10 Jul
PEG & ADC

How to use proteomics technology for cancer clinical research?

  • July 10, 2021
  • By axispharm
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The analysis of tumor genome and transcriptome has now become a tool for discovering new biomarkers, but changes ...

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08 Jul
PEG & ADC

What are the most important things to pay attention to during the preparation of antibody-conjugated drugs?

  • July 8, 2021
  • By axispharm
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Antibody conjugated drugs are formed by linking monoclonal antibodies targeting specific antigens and small molec...

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03 Jul
PEG & ADC

Proteomics Study The Molecular Mechanism Of Unraveling The Depolymerization And Ubiquitylation Of Stress Particles

  • July 3, 2021
  • By axispharm
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When the cell responds to stress, it will stop the translation process and selectively turn on the expression of ...

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30 Jun
PEG & ADC

New type of cancer immunotherapy: only kills cancer cells, not healthy cells accidentally

  • June 30, 2021
  • By axispharm
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In 2018, two pioneers in cancer immunotherapy won the Nobel Prize in Physiology or Medicine. This newly pioneered...

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26 Jun
PEG & ADC

ADC Linkers And Research Progress In Detail

  • October 7, 2023
  • By axispharm
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Linkers are not only the molecular parts that form covalent connections between antibodies and small molecular pa...

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23 Jun
PEG & ADC

Key Points To Realize The Anti-cancer Potential Of ADC Drugs

  • June 23, 2021
  • By axispharm
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The past decade has been a decade of accumulation and harvest for ADC. After the second new ADC drug Adcetris (Br...

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18 Jun
PEG & ADC

The use of fluorescent dyes and how to judge the brightness?

  • October 7, 2023
  • By axispharm
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Fluorescent dyes refer to substances that absorb light waves of a certain wavelength and emit light waves of anot...

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09 Jun
PEG & ADC

Esophageal cancer activates the ancient virus hidden in the human genome and also provides new targets for cancer treatment

  • June 9, 2021
  • By axispharm
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According to the latest global cancer burden data released by the International Agency for Research on Cancer of ...

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09 Jun
PEG & ADC

Harvard University Academician Mitragotri: Pointing out the direction for drug delivery research

  • June 9, 2021
  • By axispharm
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Drug delivery system refers to a technical system that comprehensively regulates the distribution of drugs in org...

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09 Jun
PEG & ADC

Protein Separation And Purification

  • May 29, 2023
  • By axispharm
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At the end of the research, it depends on the expression product of the group. Whether it is used for detection o...

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09 Jun
PEG & ADC

Indian Long Pepper Extract Anti-glioblastoma Drug

  • June 9, 2021
  • By axispharm
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09 Jun
PEG & ADC

Acellular Extracellular Matrix Bio-ink Build Tissue And Organ-Specific Microenvironment

  • June 9, 2021
  • By axispharm
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Tissue engineering is a revolutionary strategy to rebuild new organs or tissues through the use of various biomed...

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09 Jun
PEG & ADC

Protective agent in freeze-drying

  • June 9, 2021
  • By axispharm
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Freeze-drying is a drying method in which the drug solution that needs to be dried is frozen into a solid in adva...

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09 Jun
PEG & ADC

PEG solution therapy in treating acute hepatic encephalopathy

  • June 9, 2021
  • By axispharm
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Scientists from Baylor University Medical Center pointed out, the common drugs used to clean the patient’s intest...

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09 Jun
PEG & ADC

ADCs Enfortumab Vedotin Receives Accelerated FDA Approval

  • June 9, 2021
  • By axispharm
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Urothelial cancer accounts for more than 90% of bladder cancer. Patients diagnosed with metastatic disease have a...

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09 Jun
PEG & ADC

Dendrimer targeted therapy for cancer

  • July 14, 2022
  • By axispharm
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In view of the local invasiveness and remote metastasis characteristics of malignant tumors, the treatment effec...

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09 Jun
PEG & ADC

Cell therapy of vitamin-lipid nanoparticles to treat sepsis

  • January 12, 2023
  • By axispharm
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Sepsis is an organ dysfunction caused by the host's abnormal immune response to infection. Sepsis affects millions of people worldwid...

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09 Jun
PEG & ADC

New drug for multiple sclerosis! FDA approval of PLEGRIDY (peginterferon beta-1a)

  • August 31, 2022
  • By axispharm
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Biogen recently announced that the U.S. Food and Drug Administration (FDA) has approved Plegridy (pegylated inte...

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09 Jun
PEG & ADC

Folate receptor crystal structure-anti-cancer drug development

  • August 31, 2022
  • By axispharm
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Folic acid and vitamin B9 is an essential substance for cell growth. Indiana University scientists have revealed...

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09 Jun
PEG & ADC

Cleavable & Non- Cleavable Linkers with Antibody-Drug Conjugates

  • January 12, 2023
  • By axispharm
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Antibody-drug conjugates (ADC) have been identified as the main treatment therapy for clinical cancer treatment. The principle of ADC i...

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09 Jun
PEG & ADC

The Rise Of 3D Cell Printing Technology

  • August 31, 2022
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What if scientists no longer rely on scarce organ donations, but can build healthy new organs quickly and cheapl...

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09 Jun
PEG & ADC

PEG Polypeptides Chemical Modification

  • June 9, 2021
  • By axispharm
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A polypeptide is a compound formed by multiple amino acids connected by peptide bonds. They are ubiquitous in org...

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09 Jun
PEG & ADC

Types of anti-tumor prodrugs that exist

  • June 9, 2021
  • By axispharm
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Prodrugs is a compound through enzyme or nonenzymatic action in the body to release active matter. It has less ac...

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09 Jun
PEG & ADC

Have you used these common labeling tools?

  • January 12, 2023
  • By axispharm
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The antibody or protein labeling refers to covalently linking a target substance (enzyme, fluorescein, biotin) to an antibody or ot...

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08 Jun
PEG & ADC

FDA Approves Biogen’s New Alzheimer’s Drug Aducanumab

  • June 8, 2021
  • By axispharm
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On June 7, the US FDA announced the approval of Biogen/Eisai's Aβ (amyloid β) antibody Aduhelm (aducanumab) for t...

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29 May
PEG & ADC

Monoclonal Antibody-drug Stability Optimization

  • June 4, 2021
  • By axispharm
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Monoclonal antibody drugs are an important branch of biopharmaceuticals, which have received widespread attention...

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26 May
PEG & ADC

Can global ADC drugs-photoimmunotherapy highlight the encirclement?

  • June 9, 2021
  • By axispharm
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In recent years, antibody-drug conjugates (ADCs) have been widely sought after for their excellent clinical perfo...

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20 May
PEG & ADC

New Cancer Materials, Nano-Gold Cancer Treatments

  • August 31, 2022
  • By axispharm
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The history of human struggle with cancer is very long, from surgery, radiotherapy, and chemotherapy, to immunot...

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06 May
PEG & ADC

Development trend of G protein-coupled receptor ADC drugs

  • June 9, 2021
  • By axispharm
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G Protein-Coupled Receptors (GPCR) are a large family of seven types of transmembrane domain proteins expressed o...

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29 Apr
PEG & ADC

Azide/Alkynyl Modified Click Chemistry Reagent

  • January 12, 2023
  • By axispharm
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Click chemistry this concept was originally derived from the observation of natural products and biosynthetic pa...

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24 Apr
PEG & ADC

Growth factor PEG-fibronectin hydrogel

  • June 9, 2021
  • By axispharm
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Extracellular matrix-derived matrigel contains a variety of growth factors. And it has ECM properties that suppor...

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16 Apr
PEG & ADC

Knowledge for Ion Chromatography–HPIC

  • June 9, 2021
  • By axispharm
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Since the birth of Ion Chromatography in 1975 more than 40-year rapid development, ion chromatography has gradual...

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14 Apr
PEG & ADC

Tisotumab vedotin, a new drug for cervical cancer ADC will apply for marketing!

  • June 9, 2021
  • By axispharm
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Cervical cancer originates from the cells of the cervix. The disease is still one of the leading causes of cancer...

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10 Apr
PEG & ADC

Glutamine metabolism and cancer treatment

  • June 9, 2021
  • By axispharm
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In 1935, Hans Krebs proposed the famous tricarboxylic acid cycle (TCA), pointing out the importance of glutamine ...

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06 Apr
PEG & ADC

HER2, the first ADC drug for HER2-positive gastric cancer, approved in Japan

  • June 9, 2021
  • By axispharm
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Abstract Daiichi Sankyo recently announced that Japan’s Ministry of Hea...

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29 Mar
PEG & ADC

What is a fluorescent probe?

  • June 9, 2021
  • By axispharm
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Fluorescence is a luminescence phenomenon of photoluminescence. When certain substances are excited by light, ele...

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25 Mar
PEG & ADC

What is the click chemistry?

  • August 5, 2022
  • By axispharm
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Click chemistry is a series of reactions proposed by K. Barry Sharpless, the winner of the Nobel Prize in Chemis...

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22 Mar
PEG & ADC

Polyethylene Glycol Modification Reagent in Protein Medicine

  • June 9, 2021
  • By axispharm
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Modified PEG is also called modified polyethylene glycol, which is a PEG-modified by a chemical modification grou...

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16 Mar
PEG & ADC

What is cancer? How should we prevent it?

  • July 4, 2022
  • By axispharm
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Cancer refers to malignant tumors originating from epithelial tissues and is the most common type of malignant t...

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12 Mar
PEG & ADC

What is ADC(Antibody-drug Conjugates)?

  • July 14, 2022
  • By axispharm
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Abstract ADCs combine the high specificity of monoclonal a...

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10 Mar
PEG & ADC

What is PEG/PEG-linker?

  • October 7, 2023
  • By axispharm
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Polyethylene glycol(PEG) is an ethylene glycol polymer with a relative molecular weight of 200 to 8000 or more t...

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axispharm

AxisPharm | ADC technologies & Analytical Services. | High Purity PEG Linkers ADC Linkers Supplier.

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