Unlock the Full Potential of Your Proteomics Research with AxisPharm DIA Services

What is DIA Proteomics?

Data-Independent Acquisition (DIA) is a revolutionary approach in mass spectrometry. It provides comprehensive and quantitative data for proteomics. Unlike traditional methods, DIA allows for high-throughput protein analysis across many samples. This method offers unmatched depth, accuracy, and reproducibility, making it ideal for advanced proteomics research.

Why Choose DIA Proteomics at AxisPharm?

At AxisPharm, we focus on DIA-based proteomics to enhance the accuracy and speed of your research. We use advanced DIA technology, combined with our expert team, to deliver precise results in protein identification, quantification, and analysis.

If you’re interested in other proteomics services, explore more options at AxisPharm.

Key Benefits of DIA Proteomics

DDA vs DIA Proteomics Mass Spec Analysis

DDA vs DIA Proteomics Mass Spec Analysis

  • Comprehensive Coverage: DIA captures data from all peptides in your sample. This ensures broad protein coverage and detailed insights.
  • High Sensitivity and Accuracy: You can precisely quantify proteins, even those at low concentrations, with minimal interference from noise.
  • Enhanced Reproducibility: DIA ensures consistent and reproducible results over multiple runs. This is ideal for comparative studies or long-term research.
  • Broad Dynamic Range: DIA measures proteins across a wide concentration range, giving insights into both high-abundance and low-abundance proteins.

Our DIA Proteomics Services

1. Protein Identification

With our DIA-based protein identification, you can unlock the full range of proteins in your samples. We offer accurate identification of both known and novel proteins.

Service Highlights:

  • Advanced Mass Spectrometry: We use high-resolution equipment for accurate protein identification.
  • Bioinformatics Analysis: Powerful algorithms help us interpret the data and characterize your proteins.

2. Protein Quantification

Our DIA methods ensure precise and reproducible protein quantification. We provide detailed quantitative data to support your research goals.

Service Highlights:

  • High Sensitivity Detection: Quantify proteins with high accuracy, even those in low concentrations.
  • Dynamic Range Measurement: Capture a wide range of protein concentrations for complete analysis.

3. Post-Translational Modification (PTM) Analysis

Our DIA services help you explore post-translational modifications (PTMs) like phosphorylation and acetylation. This analysis offers deeper insights into protein function.

Service Highlights:

  • Detailed PTM Profiling: Identify and quantify various PTMs to understand their roles in protein function.
  • Specialized Techniques: We use advanced methods for accurate PTM characterization.

Why AxisPharm Stands Out

  • Expert Team: Our scientists are highly skilled in DIA proteomics and are committed to providing high-quality results.
  • State-of-the-Art Technology: We use the latest DIA technology and mass spectrometry tools to ensure the best data quality.
  • Customized Solutions: We offer tailored services to meet the specific needs of your research project.
  • Full Support: From project planning to data analysis, we provide end-to-end support for your proteomics research.

Get Started Today

Ready to advance your proteomics research with DIA? Contact AxisPharm today to discuss your project and learn how our services can support your research needs.

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    Frequently Asked Questions (FAQs)

    1. What makes DIA different from other proteomics methods?
      DIA captures comprehensive and quantitative data from all peptides in a sample, offering better coverage and reproducibility than traditional methods.

    2. How do you ensure high-quality DIA data?
      We use advanced mass spectrometry and data analysis algorithms to ensure accurate, reliable, and reproducible results.

    3. Is DIA suitable for both small and large projects?
      Yes, DIA works well for both small and large proteomics projects, delivering detailed insights no matter the project size.

    4. What types of PTMs can DIA analyze?
      DIA can analyze a wide range of PTMs, including phosphorylation, acetylation, and glycosylation.

    Related Services

    • Protein Identification Services: Learn more about our methods for accurate protein identification.
    • Quantitative Proteomics: Explore our services for reliable protein quantification and analysis.

    Ref:

    Li J, Smith LS, Zhu HJ. Data-independent acquisition (DIA): An emerging proteomics technology for analysis of drug-metabolizing enzymes and transporters. Drug Discov Today Technol. 2021 Dec;39:49-56. doi: 10.1016/j.ddtec.2021.06.006. Epub 2021 Jul 9. PMID: 34906325; PMCID: PMC8674493.

    Krasny L, Huang PH. Data-independent acquisition mass spectrometry (DIA-MS) for proteomic applications in oncology. Mol Omics. 2021 Feb 1;17(1):29-42. doi: 10.1039/d0mo00072h. Epub 2020 Oct 9. PMID: 33034323.